(±)-α-Lipoic Acid
(±)-α-Lipoic acid, also known as thioctic acid, is a naturally occurring organosulfur compound derived from octanoic acid. It serves as a coenzyme in mitochondrial energy metabolism and functions as a potent antioxidant, capable of neutralizing free radicals and regenerating other antioxidants like glutathione, vitamin C, and vitamin E. Due to its fat- and water-soluble properties, α-lipoic acid can work in various biological environments, making it highly effective in metabolic and neuroprotective applications.
Applications of (±)-α-Lipoic Acid
1. Pharmaceutical and Nutraceutical Uses
- Supports mitochondrial function by participating in enzymatic energy production.
- Additionally, it reduces oxidative stress and improves cellular defense mechanisms.
- Commonly used in dietary supplements for neuropathy, diabetes, and anti-aging benefits.
- Moreover, it enhances insulin sensitivity, making it valuable in diabetes management.
2. Antioxidant and Anti-Inflammatory Applications
- Neutralizes free radicals, reducing oxidative damage to cells and tissues.
- Furthermore, it recycles and enhances the effectiveness of glutathione, vitamin C, and vitamin E.
- Additionally, it reduces inflammation, benefiting conditions such as neurodegenerative diseases and cardiovascular health.
3. Cosmetic and Dermatological Formulations
- Incorporated in anti-aging creams and serums due to its ability to reduce wrinkles and fine lines.
- Moreover, it protects skin against UV radiation and environmental stressors.
- Additionally, it enhances skin elasticity by supporting collagen production.
4. Industrial and Research Applications
- Used as a biochemical reagent in research studies related to metabolism and cellular signaling.
- Furthermore, it is investigated for its potential in heavy metal detoxification due to its ability to chelate harmful metals.
- Additionally, it is studied for its neuroprotective effects in conditions like Alzheimer’s and Parkinson’s disease.
Features and Benefits
- Powerful Antioxidant: Effectively neutralizes free radicals and supports antioxidant regeneration
- Metabolic Support: Plays a crucial role in mitochondrial energy production
- Dual Solubility: Functions in both lipid and aqueous environments for versatile activity
- Neuroprotective Effects: May aid in reducing nerve damage and improving cognitive function
- Skin and Cellular Health: Protects against oxidative stress and enhances collagen stability
Safety and Handling
- Store in a cool, dry place, away from heat and direct sunlight
- Use protective gloves and eyewear when handling in industrial or laboratory settings
- Follow proper disposal procedures for laboratory and pharmaceutical applications
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